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Attribute
Genomics & Sequence Modeling

PrimateAI-3D

Illumina Artificial Intelligence Lab
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CategoryGenomics & Sequence Modeling
CompanyIllumina Artificial Intelligence Lab
PriceFree for academic research
StatusStatus not confirmed
AvailabilityAvailable via Illumina GitHub and Connected Analytics
Last checked20/09/2026
FeaturesTrained on benign variants identified across 233 diverse primate species, Directly incorporates 3D structural protein atomic coordinate representations, Outperforms previous variant classification tools on ClinVar and UK Biobank cohorts, Classifies variants of unknown significance (VUS) in rare genetic disorders
Entry typeAI Model & Database
Access modeOpen Access for Research
AI role3D Structural Variant Classification
Input dataNot recorded
Output dataNot recorded
Licence conditionsAcademic non-commercial use
Commercial eligibilityOpen access for non-commercial research; Illumina platform integration
Compute requirementsPre-computed genome-wide lookup table / GPU inference
ValidationNot recorded
Type3D deep learning variant pathogenicity classifier
Intended useNot recorded
CompatibilityNot recorded
ManufacturerIllumina, Inc.
Biological applicationRare disease genetic diagnosis, carrier screening, and drug target discovery
Research workflowPatient genomic variant -> query 3D pathogenicity score
Evidence levelPeer-reviewed research (Science 2023)
Integration evidencehttps://github.com/illumina/PrimateAI-3D
Laboratory handoffDirectly used in clinical genetics diagnostic reporting